Welcome to HKRESP

JOINT WEBSITE OF THE HONG KONG THORACIC SOCIETY AND THE CHEST DELEGATION HONG KONG AND MACAU

Journal & News Highlights

2010 Apr 1 - Surgical management of primary non–small-cell carcinoma of lung with synchronous solitary brain metastasis: local experience

CK Lo, CH Yu, CC Ma, KM Ko, Samuel CL Leung. Hong Kong Med J 2010;16:Epub 2010 Apr 1
OBJECTIVE. To report the surgical experience in the management of patients with synchronous primary lung cancer and solitary brain metastasis.

DESIGN. Retrospective cohort study.

SETTING. Regional hospital, Hong Kong.

PATIENTS. Seventeen patients with synchronous primary lung cancer and solitary brain metastasis were treated by pulmonary resection and neurosurgical intervention between 1994 and 2007.

RESULTS. Median patient survival was 52 months (95% confidence interval, 9-95 months) and the 5-year survival was 27%. The univariate analysis yielded no significant prognostic factor. Four out of six patients who had lymph nodes metastases developed tumour recurrence.

CONCLUSION. In view of encouraging survival results, aggressive therapy including pulmonary resection and neurosurgical intervention should be recommended for patients with synchronous presentation with primary lung cancer and solitary brain metastasis.

Weblink here